Description

11-Methoxytetrahydroyangonin is a synthetic derivative of the kavalactone family, a class of compounds known for their bioactive properties. This high-purity reference standard is critical for research and development in the pharmaceutical and nutraceutical sectors, where precise chemical characterization is paramount. It serves as a key analytical standard for quality control, method validation, and pharmacological studies targeting neurological pathways.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the identification and quantification of kavalactones in drug substances and finished products.
• Analytical Research: Essential for developing and validating HPLC, LC-MS, and GC-MS analytical methods in quality control laboratories.
• Pharmacological Studies: Used in in vitro and in vivo research to investigate biological activity, metabolism, and structure-activity relationships (SAR) of yangonin analogs.
• Nutraceutical Quality Assurance: Acts as a benchmark for standardizing and authenticating kava extracts and related herbal supplements.
• Chemical Synthesis Intermediate: Serves as a building block or precursor for the synthesis of novel derivatives with potential therapeutic applications.

Basic Information

Product Name	11-Methoxytetrahydroyangonin
CAS No.	38146-60-0
Molecular Formula	C15H18O5
Molecular Weight	278.30 g/mol
Synonyms	11-Methoxy-5,6-dihydroyangonin; 5,6-Dihydro-11-methoxyyangonin; Tetrahydro-11-methoxyyangonin; 11-Methoxy-5,6-dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one; 11-Methoxy-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; 11-Methoxytetrahydroyangonine
EINECS	Contact for details

Quality Control

Our 11-Methoxytetrahydroyangonin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.