Description

(3S,3Aβ,6Aβ,9Aβ,9Bα)-Dodecahydro-3β,9β-Dimethyl-6-Methyleneazuleno[4,5-B]Furan-2,8-Dione is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate or reference standard in sophisticated organic synthesis and pharmaceutical research. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related compounds.
• Natural Product Synthesis: Acts as a precursor in the total or semi-synthesis of complex natural products with biological activity.
• Agrochemical Research: Employed in the development of new active ingredients with specific stereochemical requirements for enhanced efficacy.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and reaction mechanisms.
• Process Chemistry: Investigated for scale-up and optimization in the production of high-value specialty chemicals.

Basic Information

Product Name	(3S,3Aβ,6Aβ,9Aβ,9Bα)-Dodecahydro-3β,9β-Dimethyl-6-Methyleneazuleno[4,5-B]Furan-2,8-Dione
CAS No.	38142-65-3
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	6-Methyleneazuleno[4,5-b]furan-2,8-dione, dodecahydro-3,9-dimethyl-, (3S,3aβ,6aβ,9aβ,9bα)-; Alantolactone Isomer; Isoalantolactone (related); Helenin derivative; (3S,3aR,6aS,9aR,9bS)-Dodecahydro-3,9-dimethyl-6-methylideneazuleno[4,5-b]furan-2,8-dione; 6-Methylene-3,9-dimethyldodecahydroazuleno[4,5-b]furan-2,8-dione
EINECS	Contact for details

Quality Control

Our (3S,3Aβ,6Aβ,9Aβ,9Bα)-Dodecahydro-3β,9β-Dimethyl-6-Methyleneazuleno[4,5-B]Furan-2,8-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.