Description

(3S)-3β-(Acetyloxy)-4β-(Angeloyloxy)-3Aβ,4,5,6,6Aα,7,9Aα,9Bβ-Octahydro-6α-Hydroxy-3,6,9-Trimethylazuleno[4,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity compound is critical for research and development in the pharmaceutical and agrochemical sectors, where precise molecular structure is paramount for efficacy and safety studies. It serves as a valuable advanced intermediate or reference standard for scientists exploring novel therapeutic agents, particularly in anti-inflammatory and anticancer research pipelines.

Application

• Pharmaceutical R&D Intermediate: Serves as a key building block or precursor in the synthesis of novel drug candidates, especially those targeting inflammatory pathways.
• Reference Standard for Analytical Testing: Used in quality control laboratories to identify, quantify, and validate the presence of this specific compound in complex mixtures via HPLC, LC-MS, or NMR.
• Bioactive Compound Research: Employed in academic and industrial research to study structure-activity relationships (SAR), mechanism of action, and pharmacological profiles of sesquiterpene lactones.
• Agrochemical Research: Investigated for potential use in developing new plant protection agents or bio-pesticides due to the inherent biological activity of its core structure.
• Natural Product Synthesis & Derivatization: Acts as a starting material for the semi-synthesis of analogs to enhance potency, stability, or bioavailability.

Basic Information

Product Name	(3S)-3β-(Acetyloxy)-4β-(Angeloyloxy)-3Aβ,4,5,6,6Aα,7,9Aα,9Bβ-Octahydro-6α-Hydroxy-3,6,9-Trimethylazuleno[4,5-B]Furan-2(3H)-One
CAS No.	38114-47-5
Molecular Formula	C22H30O7
Molecular Weight	406.47 g/mol
Synonyms	6α-Hydroxy-3β,4β-diacetoxy-9β-angeloyloxy-1-oxo-7(11)-eudesmen-8,12-olide; Alantolactone derivative; 3β-Acetoxy-4β-angeloyloxy-6α-hydroxy-3,6,9-trimethylazuleno[4,5-b]furan-2(3H)-one; Isoalantolactone acetate angelate; (3S,3aR,4S,6R,6aR,7R,9aS,9bR)-6-Hydroxy-3,6,9-trimethyl-4-[(2-methylbut-2-enoyl)oxy]-3a,4,5,6,6a,7,9a,9b-octahydro-3H-azuleno[4,5-b]furan-2,8-dione 3-acetate
EINECS	Contact for details

Quality Control

Our production of this advanced chemical intermediate adheres to strict quality management systems. Every batch is characterized and verified using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy to ensure structural integrity and purity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, purity, and impurity profiles is provided with each shipment, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.