Description

2-(2-Naphthyl)Acetyl Chloride is a specialized organic acid chloride derivative of 2-naphthylacetic acid, serving as a crucial building block in advanced organic synthesis. Its high reactivity as an acylating agent makes it indispensable for introducing the 2-naphthylacetyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is primarily sought by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and material science sectors for synthesizing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require the naphthalene backbone for bioactivity.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic semiconductors where the naphthyl group contributes to thermal stability and electronic properties.
• Peptide Modification: Acts as an acylating agent for modifying peptides and amino acid derivatives in biochemical research.
• Dye and Pigment Manufacturing: Serves as an intermediate in the production of high-performance naphthalene-based dyes and organic pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.

Basic Information

Product Name	2-(2-Naphthyl)Acetyl Chloride
CAS No.	37859-25-9
Molecular Formula	C₁₂H₉ClO
Molecular Weight	204.65 g/mol
Synonyms	2-Naphthylacetyl Chloride; (2-Naphthyl)acetyl Chloride; 2-(2-Naphthyl)acetyl Chloride; 2-Naphthaleneacetyl Chloride; 2-Naphthylacetic Acid Chloride; 2-(Naphthalen-2-yl)acetyl Chloride; α-Naphthylacetyl Chloride (ambiguous, specify 2-isomer); 2-(2-Naphthyl)ethanoyl Chloride
EINECS	Contact for details

Quality Control

Our 2-(2-Naphthyl)Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, heat, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.