Description

(14R)-Grayanotoxane-2α,3β,5,6β,10,14,16-Heptol CAS NO 37720-87-9 is a complex diterpenoid natural product belonging to the grayanotoxin family. This compound is of significant interest for its role as a key reference standard and a crucial intermediate in advanced phytochemical and pharmacological research. It is primarily sought by research institutions and pharmaceutical development companies engaged in neurobiological studies, natural product synthesis, and toxicological profiling. The high-purity material is essential for ensuring accurate analytical results and reproducible experimental outcomes.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of grayanotoxin-related compounds in drug discovery and quality control laboratories.
• Neuroscience Research: Serves as a critical tool for studying voltage-gated sodium channel modulation and related neurophysiological mechanisms.
• Natural Product Isolation & Synthesis: Acts as a benchmark for the isolation, purification, and total synthesis of complex grayanane diterpenoids.
• Toxicology & Safety Assessment: Employed as an analytical standard in the safety evaluation of food products (e.g., honey) and botanical preparations for potential grayanotoxin contamination.
• Academic Research: Utilized in university and institutional labs for structural-activity relationship (SAR) studies and chemical ecology investigations.
• Biochemical Reagent: Potential use in developing assay kits or as a specialized reagent for probing specific biological pathways.

Basic Information

Product Name	(14R)-Grayanotoxane-2α,3β,5,6β,10,14,16-Heptol
CAS No.	37720-87-9
Molecular Formula	C20H34O7
Molecular Weight	386.48 g/mol
Synonyms	Grayanotoxane-2α,3β,5,6β,10,14,16-heptol, (14R)-; Grayanotoxin III; Acetylandromedol; Rhodojaponin III; 2α,3β,5,6β,10,14,16-Heptahydroxygrayanane; Andromedotoxin derivative; (2α,3β,5,6β,10,14,16)-Grayanotoxane-heptol
EINECS	Contact for details

Quality Control

Our (14R)-Grayanotoxane-2α,3β,5,6β,10,14,16-Heptol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with various pharmacopeial and research-grade standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.