Description

(R)-Piperidine-3-Carboxylic Acid Ethyl Ester Hydrochloride is a high-purity chiral building block essential for pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, particularly those targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a precursor for constructing complex molecules with defined stereochemistry in medicinal chemistry.
• API Development: Integral in the research and scale-up phases for developing new Active Pharmaceutical Ingredients.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Academic & Industrial Research: Employed in exploratory chemistry for developing new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	(R)-Piperidine-3-Carboxylic Acid Ethyl Ester Hydrochloride
CAS No.	37675-19-7
Molecular Formula	C8H16ClNO2
Molecular Weight	193.67 g/mol
Synonyms	(R)-Ethyl Nipecotate Hydrochloride; (R)-3-Carbethoxypiperidine Hydrochloride; (R)-3-Piperidinecarboxylic Acid Ethyl Ester Hydrochloride; (R)-Nipecotic Acid Ethyl Ester Hydrochloride; (R)-1,2,3,6-Tetrahydropyridine-3-carboxylic Acid Ethyl Ester Hydrochloride; (R)-3-Ethoxycarbonylpiperidine Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Piperidine-3-Carboxylic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.