Description

Ethyl (3S)-Piperidine-3-Carboxylate is a high-purity chiral building block of significant importance in modern synthetic chemistry. This compound serves as a critical intermediate for the development of novel, stereochemically defined active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of piperidine-based drug candidates, including potential treatments for central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity and environmental profile.
• Catalyst and Ligand Synthesis: Serves as a precursor for creating chiral catalysts and ligands used in asymmetric synthesis to induce enantioselectivity.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for research and development purposes.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	Ethyl (3S)-Piperidine-3-Carboxylate
CAS No.	37675-18-6
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(3S)-3-Piperidinecarboxylic acid ethyl ester; Ethyl (S)-3-piperidinecarboxylate; (S)-Ethyl nipecotate; (S)-Ethyl 3-piperidinecarboxylate; (S)-1-Ethyl 3-piperidinecarboxylate; (3S)-1-Ethylpiperidine-3-carboxylate; L-Nipecotic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl (3S)-Piperidine-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to meet the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.