Description

4-(Piperazin-1-yl)butanoic acid is a versatile bifunctional organic compound featuring both a piperazine ring and a carboxylic acid group, making it a valuable intermediate in advanced chemical synthesis. Its structure is critical for constructing complex molecules with specific biological or material properties. This compound is primarily sought after by the pharmaceutical and agrochemical industries for research, development, and production of active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Linker Chemistry: Serves as a spacer or linker molecule in the creation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Chemical Research & Development: Essential reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Ligand Synthesis for Catalysis: Used to prepare complex ligands for metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	4-(Piperazin-1-yl)butanoic Acid
CAS No.	37528-82-8
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	4-(1-Piperazinyl)butanoic Acid; 4-Piperazin-1-yl-butyric Acid; 4-Piperazin-1-ylbutyric Acid; 1-(3-Carboxypropyl)piperazine; Butanoic acid, 4-(1-piperazinyl)-; NSC 169865; γ-(1-Piperazinyl)butyric Acid
EINECS	Contact for details

Quality Control

Our 4-(Piperazin-1-yl)butanoic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee reliable quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.