Description

(R)-2-Hydroxy-2-Methylbutyric Acid CAS NO 37505-02-5 is a high-purity chiral building block and intermediate of significant value in asymmetric synthesis. Its enantiomeric purity makes it a critical component for the production of optically active pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Synthesis of chiral active pharmaceutical ingredients (APIs) and drug candidates.
• Building block for asymmetric catalysts and ligands used in organic synthesis.
• Intermediate in the production of agrochemicals, such as herbicides and fungicides.
• Key starting material for flavor and fragrance compounds requiring specific stereochemistry.
• Chiral resolving agent in the separation of enantiomers.
• Research and development of novel bioactive molecules in academic and industrial settings.

Basic Information

Product Name	(R)-2-Hydroxy-2-Methylbutyric Acid
CAS No.	37505-02-5
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(R)-2-Hydroxy-2-methylbutanoic acid; (R)-2-Methyl-2-hydroxybutyric acid; D-2-Hydroxy-2-methylbutyric acid; (R)-HMB; (2R)-2-Hydroxy-2-methylbutanoic acid; (R)-α-Hydroxyisovaleric acid; (R)-2-Methylbutyric acid 2-ol
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxy-2-Methylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood or well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.