Description

Tetrahydrocannabinolic Acid CAS NO 37347-91-4 is the primary acidic precursor to the well-known psychoactive compound δ9-Tetrahydrocannabinol (δ9-THC). This compound is of significant commercial and research interest as a key marker for the quality and standardization of cannabis-derived products. It is essential for manufacturers and analytical laboratories in the pharmaceutical, nutraceutical, and cannabinoid research sectors seeking to develop and validate high-purity reference standards and active ingredients.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the quantitative and qualitative analysis of cannabis plant material and extracts.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the research and development of novel cannabinoid-based therapeutics, where its decarboxylation to THC is a critical step.
• Nutraceutical & Cosmetic Formulation: Incorporated into high-end wellness products where the acidic cannabinoid profile is desired for its purported unique properties.
• Analytical Research & Method Development: Essential for calibrating HPLC, GC-MS, and other analytical instruments to ensure accurate potency testing and compliance.
• Biosynthetic Pathway Studies: Used in biochemical research to study the enzymatic synthesis and metabolism of cannabinoids in the cannabis plant.
• Quality Control & Assurance: Provides a benchmark for manufacturers to verify the authenticity, purity, and consistency of raw cannabis extracts and finished products.

Basic Information

Item	Details
Product Name	Tetrahydrocannabinolic Acid
CAS No.	37347-91-4
Molecular Formula	C22H30O4
Molecular Weight	358.48 g/mol
Synonyms	THCA; δ9-Tetrahydrocannabinolic Acid; (-)-δ9-Tetrahydrocannabinolic Acid A; 2-Carboxy-δ9-tetrahydrocannabinol; Cannabinoic Acid; 1,3-Benzenediol, 2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-, 2-carboxy derivative
EINECS	Contact for details

Quality Control

Our Tetrahydrocannabinolic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
δ9-THC Content	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.