Description

3-(Trimethylsilyl)Propionic Acid Sodium Salt is a versatile organosilicon compound widely used as a chemical reference standard and a key intermediate in advanced synthesis. Its value lies in its unique trimethylsilyl-protected carboxylic acid group, which provides stability and reactivity for specialized chemical transformations. This product is essential for researchers and manufacturers in the pharmaceutical, analytical chemistry, and material science industries, particularly for NMR spectroscopy and the development of silicon-containing polymers.

Application

• NMR Spectroscopy: Primarily used as an internal chemical shift reference standard (e.g., TSP-d4) for proton and carbon-13 NMR in aqueous and deuterated solvent systems.
• Pharmaceutical Intermediates: Serves as a protected carboxylic acid building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Polymer & Material Science: Acts as a monomer or modifying agent in the production of silicone-based polymers, coatings, and advanced functional materials.
• Bioconjugation & Proteomics: Utilized in chemical biology for labeling and modifying biomolecules due to its reactive sodium carboxylate group.
• Analytical Chemistry: Employed as a calibration standard and reagent in various chromatographic and mass spectrometric methods.
• Organic Synthesis: Functions as a key intermediate for introducing the trimethylsilylpropionic acid moiety into larger organic frameworks.

Basic Information

Product Name	3-(Trimethylsilyl)Propionic Acid Sodium Salt
CAS No.	37013-20-0
Molecular Formula	C6H13NaO2Si
Molecular Weight	168.24 g/mol
Synonyms	Sodium 3-(Trimethylsilyl)propionate; Sodium Trimethylsilylpropionate; TSP; 3-(Trimethylsilyl)propanoic Acid Sodium Salt; (3-Trimethylsilyl)propionic Acid Sodium Salt; Sodium 3-(Trimethylsilyl)propanoate; TSP-d4 (deuterated form); NMR Reference Standard TSP; 2,2,3,3-D4-3-(Trimethylsilyl)propionic Acid Sodium Salt
EINECS	253-324-8

Quality Control

Our 3-(Trimethylsilyl)Propionic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high purity and consistency suitable for research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Solubility (in D2O)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.