Description

1-Cyclopropylcarbonyl-4-Phenylpiperazine Hydrochloride is a high-purity, synthetically derived piperazine derivative used as a critical pharmaceutical intermediate. This compound matters for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers seeking reliable building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Preclinical Studies: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Chemical Synthesis: Acts as a versatile precursor for further functionalization to create libraries of related piperazine-based compounds.

Basic Information

Product Name	1-Cyclopropylcarbonyl-4-Phenylpiperazine Hydrochloride
CAS No.	37012-00-3
Molecular Formula	C14H19N2O·HCl
Molecular Weight	266.78 g/mol
Synonyms	N-Cyclopropylcarbonyl-4-phenylpiperazine hydrochloride; 1-(Cyclopropylcarbonyl)-4-phenylpiperazine hydrochloride; 4-Phenyl-1-(cyclopropylcarbonyl)piperazine hydrochloride; N-(4-Phenylpiperazin-1-yl)cyclopropanecarboxamide hydrochloride; Cyclopropanecarboxylic acid (4-phenylpiperazin-1-yl)amide hydrochloride; CPCP hydrochloride; 1-Cyclopropanecarbonyl-4-phenylpiperazine HCl
EINECS	Contact for details

Quality Control

Our 1-Cyclopropylcarbonyl-4-Phenylpiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.