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(20ξ)-3β,23-Bis(Acetyloxy)-20-Hydroxy-12-Oxo-5α-Lanost-9(11)-En-18-Oic Acid γ-Lactone CAS NO 36872-81-8
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CAS No.:36872-81-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(20ξ)-3β,23-Bis(Acetyloxy)-20-Hydroxy-12-Oxo-5α-Lanost-9(11)-En-18-Oic Acid γ-Lactone is a highly functionalized lanostane-type triterpenoid derivative, serving as a critical advanced intermediate in pharmaceutical research and synthesis. Its complex structure, featuring acetyl, hydroxyl, oxo, and lactone functional groups, makes it a valuable scaffold for developing novel bioactive compounds. This compound is primarily utilized by research institutions and pharmaceutical companies focused on anti-inflammatory, antiviral, and metabolic disorder drug discovery programs.
Application
- Pharmaceutical Intermediate: Key synthetic precursor for the development of novel triterpenoid-based therapeutics targeting inflammation and metabolic pathways.
- Biochemical Research: Used as a reference standard or probe in studies investigating lanostane biosynthesis and enzyme inhibition.
- Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies and the synthesis of analogs with potential pharmacological activity.
- Natural Product Synthesis: Intermediate in the semi-synthesis or total synthesis of complex natural products derived from lanostane skeletons.
- High-Purity Reference Material: Supplied as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
Basic Information
| Item | Details |
|---|---|
| Product Name | (20ξ)-3β,23-Bis(Acetyloxy)-20-Hydroxy-12-Oxo-5α-Lanost-9(11)-En-18-Oic Acid γ-Lactone |
| CAS No. | 36872-81-8 |
| Molecular Formula | C34H48O8 |
| Molecular Weight | 584.75 g/mol |
| Synonyms | 3β,23-Diacetoxy-20-hydroxy-12-oxo-5α-lanost-9(11)-en-18-oic acid γ-lactone; 20-Hydroxy-3β,23-diacetoxy-12-oxo-5α-lanost-9(11)-en-18-oic acid γ-lactone; Lanostane triterpenoid lactone derivative; (20ξ)-3β,23-Bis(acetyloxy)-20-hydroxy-12-oxo-5α-lanost-9(11)-en-18-oic acid γ-lactone; 3β,23-Diacetyl-20-hydroxy-12-oxolanost-9(11)-en-18-oic acid γ-lactone |
| EINECS | Contact for details |
Quality Control
Our (20ξ)-3β,23-Bis(Acetyloxy)-20-Hydroxy-12-Oxo-5α-Lanost-9(11)-En-18-Oic Acid γ-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) standards where applicable.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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