Description

4-(Trifluoromethoxy)Benzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in introducing the trifluoromethoxybenzoyl moiety, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring the trifluoromethoxybenzoyl group to modulate bioactivity and pharmacokinetics.
• Agrochemical Synthesis: Used in manufacturing advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing liquid crystal compounds used in display technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce fluorinated aromatic units into polymers, enhancing thermal and chemical resistance.
• Organic Synthesis & Research: A fundamental reagent for amide and ester formation via nucleophilic acyl substitution reactions in academic and industrial R&D laboratories.
• Dye and Pigment Industry: Intermediate in the production of specialized dyes and pigments with improved lightfastness and stability.

Basic Information

Item	Detail
Product Name	4-(Trifluoromethoxy)Benzoyl Chloride
CAS No.	36823-88-8
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	p-(Trifluoromethoxy)benzoyl chloride; 4-(Trifluoromethoxy)benzoic acid chloride; α,α,α-Trifluoro-p-anisoyl chloride; 4-(Trifluoromethoxy)benzoyl chloride; 4-(Trifluoromethoxy)-benzoic acid chloride; Benzoic acid, 4-(trifluoromethoxy)-, chloride; TFMOBC
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C or as specified on the label. Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.