Description

3β-Acetoxy-1β,5,14,16β-Tetrahydroxy-19-Oxo-5β-Bufa-20,22-Dienolide CAS NO 36405-85-3 is a highly specialized bufadienolide derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of cardiac glycosides and novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in advanced synthetic chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cardiac glycosides and other bioactive steroid derivatives for preclinical research.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies targeting Na+/K+-ATPase enzyme activity and related cellular pathways.
• Academic Research: Employed in university and institutional labs for structure-activity relationship (SAR) studies and the development of new synthetic methodologies for complex natural products.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex bufadienolide analogs with potential therapeutic applications.

Basic Information

Item	Details
Product Name	3β-Acetoxy-1β,5,14,16β-Tetrahydroxy-19-Oxo-5β-Bufa-20,22-Dienolide
CAS No.	36405-85-3
Molecular Formula	C₂₆H₃₄O₉
Molecular Weight	490.54 g/mol
Synonyms	19-Oxocinobufagin 3-acetate; 3β-Acetoxy-1β,5,14,16β-tetrahydroxy-19-oxo-5β-bufa-20,22-dienolide; 3-O-Acetyl-19-oxocinobufagin; 19-Oxocinobufagin 3-O-acetate; Bufadienolide derivative 36405-85-3; 5β-Bufa-20,22-dienolide, 3β-acetoxy-1β,5,14,16β-tetrahydroxy-19-oxo-
EINECS	Contact for details

Quality Control

Our 3β-Acetoxy-1β,5,14,16β-Tetrahydroxy-19-Oxo-5β-Bufa-20,22-Dienolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.