Description

2-Methyl-2-Phenylpropanoyl Chloride is a versatile and highly reactive acid chloride derivative. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the bulky 2-methyl-2-phenylpropanoyl moiety. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical sectors for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key reagent for the synthesis of amides, esters, and other derivatives used in active pharmaceutical ingredient (API) development.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring the incorporation of a sterically hindered aromatic group.
• Polymer Chemistry: Acts as a monomer or modifying agent for specialty polymers, including polyamides and polyesters, to impart specific thermal or mechanical properties.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and photographic chemicals.
• Cross-Coupling Reactions: Serves as a substrate in various metal-catalyzed coupling reactions to construct complex molecular architectures.
• Laboratory Research: Utilized in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Product Name	2-Methyl-2-Phenylpropanoyl Chloride
CAS No.	36293-05-7
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	2-Methyl-2-phenylpropionyl chloride; α,α-Dimethylphenylacetyl chloride; Pivalophenone chloride; 2,2-Dimethyl-2-phenylacetyl chloride; Neopentylphenone chloride; 2-Phenylisobutyryl chloride; 2-Methyl-2-phenylpropanoic acid chloride; 36293-05-7
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-Phenylpropanoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including assay by titration and impurity profiling by GC/HPLC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/Titration)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC/HPLC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.