Description

Ethyl Malonyl Chloride is a versatile and highly reactive acid chloride derivative of malonic acid, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the ethyl malonyl moiety, enabling the construction of complex molecular frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing β-ketoester or malonate-derived structures.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators that incorporate malonate ester functionalities.
• Peptide Mimetics & Conjugation: Employed as a coupling agent or linker for modifying peptides and creating peptide-drug conjugates.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, coatings, and dendrimers.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and colorants.

Basic Information

Product Name	Ethyl Malonyl Chloride
CAS No.	36239-09-5
Molecular Formula	C5H7ClO3
Molecular Weight	150.56 g/mol
Synonyms	Malonyl chloride, ethyl ester; Ethoxycarbonylacetyl chloride; 3-Ethoxy-3-oxopropanoyl chloride; Monoethyl malonyl chloride; Ethyl ester of malonyl chloride; Propanoyl chloride, 3-ethoxy-3-oxo-; Ethyl 3-chloro-3-oxopropanoate; Carbonyl chloride, (ethoxycarbonyl)methyl-
EINECS	Contact for details

Quality Control

Our Ethyl Malonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 1.0% (any single impurity)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.