Description

cis-4-Hydroxy-3-Methylpiperidine CAS NO 36173-52-1 is a high-purity, functionalized piperidine derivative that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry of the hydroxyl and methyl groups, which is critical for imparting specific biological activity and physicochemical properties to final compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries who require high-quality, stereochemically defined intermediates for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry influences efficacy.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: A valuable building block in academic and industrial R&D for exploring new chemical entities and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	cis-4-Hydroxy-3-Methylpiperidine
CAS No.	36173-52-1
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	3-Methyl-4-hydroxypiperidine (cis); (3R,4S)-3-Methylpiperidin-4-ol; (3S,4R)-3-Methylpiperidin-4-ol; cis-3-Methyl-4-piperidinol; 4-Hydroxy-3-methylpiperidine; 4-Piperidinol, 3-methyl-, cis-; 36173-52-1
EINECS	Contact for details

Quality Control

Our cis-4-Hydroxy-3-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.