Description

Ethyl 5-Bromo-2-Pyrazinecarboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its bromine and ester functionalities enable precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex pyrazine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require pyrazine core structures.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts due to its modifiable functional groups.
• Material Science Research: Serves as a building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	Ethyl 5-Bromo-2-Pyrazinecarboxylate
CAS No.	36070-83-4
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	5-Bromo-2-pyrazinecarboxylic acid ethyl ester; Ethyl 5-bromopyrazine-2-carboxylate; 5-Bromopyrazine-2-carboxylic Acid Ethyl Ester; 2-Pyrazinecarboxylic acid, 5-bromo-, ethyl ester; 36070-83-4; Ethyl 5-bromo-2-pyrazinecarboxylate; 5-Bromo-2-(ethoxycarbonyl)pyrazine
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-Pyrazinecarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.