Description

5-Chloro-Pyrazine-2-Carboxylic Acid is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its reactive carboxylic acid and chloro substituents, which enable diverse functionalization and coupling reactions. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the construction of organic electronic materials, such as conductive polymers and molecular semiconductors.
• Custom Synthesis & Contract Manufacturing: A key building block for custom chemical synthesis services and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Chloro-Pyrazine-2-Carboxylic Acid
CAS No.	36070-80-1
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54 g/mol
Synonyms	5-Chloropyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 5-chloro-; 5-Chloro-2-pyrazinecarboxylic acid; 5-Chloro-2-carboxypyrazine; 36070-80-1; 5-Chloropyrazinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.