Description

2-Chloro-5-Cyanopyrazine is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis. Its unique bifunctional structure, featuring both a reactive chloro substituent and a cyano group, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and catalysts used in metal-organic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for creating labeled compounds and probes for studying biological mechanisms.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Chloro-5-Cyanopyrazine
CAS No.	36070-75-4
Molecular Formula	C5H2ClN3
Molecular Weight	139.54 g/mol
Synonyms	5-Cyano-2-chloropyrazine; 2-Chloro-5-cyanopyrazine; 2-Chloropyrazine-5-carbonitrile; 36070-75-4; Pyrazine, 2-chloro-5-cyano-; 2-Chloro-5-pyrazinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Cyanopyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.