Description

3,4-Xylyl Chloroformate is a specialized organic reagent belonging to the chloroformate ester class, identified by CAS NO 36018-20-9. This compound serves as a versatile and reactive intermediate, crucial for introducing the 3,4-dimethylbenzyloxycarbonyl (Dmz) protecting group in complex organic syntheses. It is primarily needed by research institutions and industrial manufacturers engaged in the production of pharmaceuticals, agrochemicals, and advanced materials, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in peptide and nucleoside chemistry.
• Amino Acid Protecting Agent: Used to temporarily protect amine functional groups during multi-step synthetic sequences, leveraging its orthogonal deprotection properties.
• Agrochemical Synthesis: Intermediate in the manufacture of certain herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Monomer or modifying agent for producing specialty polymers with tailored properties.
• Chemical Research: Essential reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel molecular entities.
• Dye and Pigment Production: Used in the synthesis of complex organic colorants and functional dyes.

Basic Information

Product Name	3,4-Xylyl Chloroformate
CAS No.	36018-20-9
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	3,4-Dimethylbenzyl Chloroformate; (3,4-Dimethylphenyl)methyl Carbonochloridate; Dmz-Cl; 3,4-Xylyl Chloroformate; Chloroformic Acid 3,4-Dimethylbenzyl Ester; 3,4-Dimethylbenzyloxycarbonyl Chloride; 36018-20-9; (3,4-Dimethylbenzyl) Chloroformate
EINECS	Contact for details

Quality Control

Our 3,4-Xylyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing specific batch results are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.