Description

Propargyl Chloroformate CAS NO 35718-08-2 is a versatile and highly reactive chloroformate ester, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the propargyl group and a reactive carbonyl chloride moiety, enabling efficient derivatization and protection strategies. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), polymer precursors, and fine chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of complex drug molecules, particularly for introducing propargyl functionalities used in click chemistry and further modifications.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring propargyl-based active components.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the production of specialty polymers, resins, and coatings with tailored properties.
• Peptide & Protein Modification: Employed as a coupling agent or protecting group reagent in peptide synthesis and bioconjugation techniques.
• Organic Synthesis Reagent: Fundamental building block for constructing carbon-carbon bonds and synthesizing heterocyclic compounds, alkynes, and carbonates.
• Material Science Research: Utilized in developing novel materials, including dendrimers, functionalized surfaces, and advanced composites.

Basic Information

Product Name	Propargyl Chloroformate
CAS No.	35718-08-2
Molecular Formula	C4H3ClO2
Molecular Weight	118.52 g/mol
Synonyms	Propargyl Chloroformate; Propargyloxycarbonyl Chloride; Chloroformic Acid Propargyl Ester; 2-Propynyl Chloroformate; Propargyl Carbonochloridate; 2-Propynyl Carbonochloridate; Propargyl Chlorocarbonate; 2-Propynyloxycarbonyl Chloride
EINECS	Contact for details

Quality Control

Our Propargyl Chloroformate is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maintain stability and purity. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.