Description

Tolmetin Sodium is the sodium salt form of the non-steroidal anti-inflammatory drug (NSAID) tolmetin. This compound is a critical active pharmaceutical ingredient (API) valued for its potent anti-inflammatory, analgesic, and antipyretic properties. It is primarily required by pharmaceutical manufacturers for the formulation of prescription medications used to manage pain and inflammation associated with conditions like rheumatoid arthritis and osteoarthritis.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of prescription anti-inflammatory and analgesic drugs.
• Tablet Formulation: Used in the production of solid oral dosage forms, such as immediate-release and delayed-release tablets.
• Capsule Formulation: Incorporated into hard gelatin or other capsule formats for oral delivery.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for new NSAID formulations or delivery systems.
• Analytical Standard: Used as a high-purity standard in quality control laboratories for HPLC, UV, and other analytical methods.

Basic Information

Product Name	Tolmetin Sodium
CAS No.	35711-34-3
Molecular Formula	C15H14NNaO3
Molecular Weight	279.27 g/mol
Synonyms	Tolmetin Sodium Salt; 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid sodium salt; Sodium tolmetin; McN-2559; Tolectin (brand name reference); Tolmetin Na; (1-Methyl-5-(p-toluoyl)-1H-pyrrol-2-yl)acetic acid sodium salt
EINECS	Contact for details

Quality Control

Our Tolmetin Sodium is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles. A Certificate of Analysis (COA) documenting compliance with relevant pharmacopeial standards (such as USP or in-house pharmaceutical grade specifications) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Limits	Meets Ph. Eur./USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.