Description

2-Chloro-3-Hydroxyquinoxaline is a versatile and high-value heterocyclic building block, primarily used as a key intermediate in the synthesis of complex organic molecules. Its unique quinoxaline core, functionalized with both chloro and hydroxy groups, makes it an essential precursor for developing advanced materials and active pharmaceutical ingredients (APIs). This compound is of critical importance to research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Serves as a key precursor in the manufacture of advanced pesticides, herbicides, and fungicides, leveraging the quinoxaline scaffold's bioactivity.
• Organic Electronic Materials: Used in research and development of organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its electron-deficient aromatic structure.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing quinoxaline-based dyes and pigments, which offer excellent lightfastness and color properties.
• Coordination Chemistry & Ligand Synthesis: The hydroxy and nitrogen donor atoms make it a useful starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions, synthesizing libraries of compounds for screening, and methodological studies.

Basic Information

Product Name	2-Chloro-3-Hydroxyquinoxaline
CAS No.	35676-70-1
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	3-Hydroxy-2-chloroquinoxaline; 2-Chloro-3-quinoxalinol; 2-Chloro-3-hydroxy-quinoxaline; Quinoxalin-3-ol, 2-chloro-; 2-Chloroquinoxalin-3-ol; 2-Chloro-3(1H)-quinoxalinone (tautomer)
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Hydroxyquinoxaline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. Standard quality parameters include identity confirmation by spectroscopic methods and purity assessment by HPLC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions to maintain product integrity during long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.