Description

2H-1,3-Oxazine-3(4H)-Carbonyl Chloride, Dihydro-6-Methyl- (9Ci) is a specialized heterocyclic building block and acylating agent of significant interest in advanced organic synthesis. Its core value lies in its reactive carbonyl chloride group, which enables efficient introduction of the oxazine moiety into complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those containing dihydrooxazine or related heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in research and development for creating new herbicides, fungicides, or insecticides that incorporate the methyl-dihydrooxazine structure.
• Organic Synthesis Reagent: Serves as a versatile acylating agent in academic and industrial laboratories for the preparation of amides, esters, and other derivatives from the corresponding oxazine carboxylic acid.
• Material Science Research: Potential monomer or precursor for developing specialized polymers or functional materials with unique chemical properties.
• Chemical Biology Probe Development: Useful for synthesizing activity-based probes or labeled compounds to study biological pathways and enzyme functions.

Basic Information

Product Name	2H-1,3-Oxazine-3(4H)-Carbonyl Chloride, Dihydro-6-Methyl- (9Ci)
CAS No.	35627-13-5
Molecular Formula	C6H8ClNO2
Molecular Weight	161.59 g/mol
Synonyms	6-Methyl-3,4-dihydro-2H-1,3-oxazine-3-carbonyl chloride; 6-Methyl-3,4-dihydro-2H-1,3-oxazine-3-carboxylic acid chloride; 6-Methyl-2H-1,3-oxazine-3(4H)-carbonyl chloride; Dihydro-6-methyl-2H-1,3-oxazine-3(4H)-carbonyl chloride; 3-Carboxyldihydro-6-methyl-2H-1,3-oxazine chloride; 35627-13-5 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 2H-1,3-Oxazine-3(4H)-Carbonyl Chloride, Dihydro-6-Methyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including purity assay and identity confirmation. Certificates of Analysis (COA) detailing specific results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic and moisture-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.