Description

Buflomedil Hydrochloride is a pharmaceutical active ingredient belonging to the class of vasodilators. It is a critical intermediate and active pharmaceutical ingredient (API) used in the manufacture of medications designed to improve peripheral and cerebral blood circulation. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for vascular disorders. Our high-purity Buflomedil Hydrochloride CAS NO 35543-24-9 ensures consistent quality and reliable performance in downstream formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for the treatment of peripheral vascular diseases.
• Vasodilator Formulations: Key component in medications aimed at improving blood flow in conditions like intermittent claudication and Raynaud's phenomenon.
• Cerebral Circulation Therapy: Used in the development of drugs targeting cognitive disorders associated with reduced cerebral blood flow.
• Research & Development: Serves as a reference standard and building block in pharmacological and pharmacokinetic studies.
• Generic Drug Manufacturing: Sourced by generic pharmaceutical companies for the production of cost-effective therapeutic equivalents.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for circulatory issues in animals.

Basic Information

Product Name	Buflomedil Hydrochloride
CAS No.	35543-24-9
Molecular Formula	C17H25NO4 • HCl
Molecular Weight	343.85 g/mol
Synonyms	2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone Hydrochloride; Buflomedil HCl; Loftyl; Fonzylane; Bufedil; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone Hydrochloride; Butyrophenone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our Buflomedil Hydrochloride is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical applications, with testing aligned with common pharmacopeial guidelines. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every batch to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.