Description

(S)-α-Dimethylamino-n-[(3R,4S,7S)-3-Isopropyl-5,8-Dioxo-7-Benzyl-2-Oxa-6,9-Diazabicyclo[10.2.2]Hexadeca-10,12,14(1),15-Tetren-4-Yl]Benzenepropanamide is a complex, stereochemically defined bicyclic compound that serves as a critical advanced pharmaceutical intermediate or building block in organic synthesis. Its intricate molecular architecture, featuring multiple chiral centers and a fused heterocyclic system, makes it invaluable for constructing sophisticated target molecules with high precision. This compound is primarily utilized by research institutions and pharmaceutical developers engaged in the synthesis of novel therapeutic agents, particularly in areas requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with targeted biological activity.
• Asymmetric Synthesis: Employed as a sophisticated precursor or reagent in stereoselective synthesis to introduce specific chiral elements into larger molecular frameworks.
• Process Chemistry Development: Serves as a reference standard or a critical intermediate during the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Potential use in the development of molecular probes for studying biological pathways and protein interactions due to its complex, drug-like structure.

Basic Information

Product Name	(S)-α-Dimethylamino-n-[(3R,4S,7S)-3-Isopropyl-5,8-Dioxo-7-Benzyl-2-Oxa-6,9-Diazabicyclo[10.2.2]Hexadeca-10,12,14(1),15-Tetren-4-Yl]Benzenepropanamide
CAS No.	35467-41-5
Molecular Formula	C33H41N3O4
Molecular Weight	543.70 g/mol
Synonyms	(S)-α-(Dimethylamino)-N-[(3R,4S,7S)-3-(1-methylethyl)-5,8-dioxo-7-(phenylmethyl)-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-1(14),10,12,15-tetraen-4-yl]benzenepropanamide; (3R,4S,7S)-4-[[(2S)-3-(Dimethylamino)-1-oxo-3-phenylpropyl]amino]-3-(1-methylethyl)-7-(phenylmethyl)-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-1(14),10,12,15-tetraene-5,8-dione; Complex Bicyclic Diamide Derivative; Advanced Chiral Bicyclic Intermediate.
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing key parameters such as chiral purity, assay, and impurity profiles determined by advanced analytical techniques including HPLC and NMR. We support our clients with the documentation and specifications required for their regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.