Description

2-Norbornanecarbonyl Chloride is a specialized bicyclic acid chloride derivative, serving as a crucial high-purity building block in advanced organic synthesis. Its unique norbornane framework provides a rigid, three-dimensional structure that is highly valuable for creating complex molecules with specific steric and electronic properties. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the norbornane moiety or as an acylating agent under controlled conditions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring rigid, lipophilic scaffolds to modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the norbornane structure can enhance environmental stability and target specificity.
• Polymer Science & Advanced Materials: Serves as a monomer or cross-linking agent for creating specialty polymers with high thermal stability, unique optical properties, or specific mechanical characteristics.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Organic Synthesis Reagent: Functions as a reactive acyl chloride for amide bond formation, esterification, and Friedel-Crafts acylation reactions in complex molecule construction.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science R&D for exploring new chemical spaces and structure-activity relationships.

Basic Information

Product Name	2-Norbornanecarbonyl Chloride
CAS No.	35202-90-5
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	Bicyclo[2.2.1]heptane-2-carbonyl chloride; Norbornane-2-carbonyl chloride; 2-Bicyclo[2.2.1]heptanecarbonyl chloride; endo-Norbornane-2-carbonyl chloride; 2-Norbornanecarboxylic acid chloride; Norbornyl-2-carbonyl chloride; 2-Carboxynorbornane chloride
EINECS	Contact for details

Quality Control

Our 2-Norbornanecarbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Purity (GC Area %)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.