Description

2-Bromo-4-(1,3-Dioxoisoindolin-2-Yl)Butanoic Acid is a specialized brominated organic acid derivative featuring a phthalimide-protected amine functionality. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly for the introduction of functionalized alkyl chains. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Mimetics & Linker Chemistry: Used to incorporate bromoalkyl acid segments into peptides or as a cleavable linker in prodrug design.
• Organic Synthesis Building Block: Serves as a versatile reagent for nucleophilic substitution reactions, leveraging the bromine atom for further functionalization.
• Protecting Group Strategy: The 1,3-dioxoisoindolin-2-yl (phthalimido) group acts as a protected amine, which can be deprotected under specific conditions (e.g., hydrazine).
• Material Science Research: Potential monomer or functionalizing agent in the development of specialized polymers with tailored properties.
• Agrochemical Synthesis: Intermediate in the research and development of novel crop protection agents.

Basic Information

Item	Detail
Product Name	2-Bromo-4-(1,3-Dioxoisoindolin-2-Yl)Butanoic Acid
CAS No.	35197-64-9
Molecular Formula	C12H10BrNO4
Molecular Weight	312.12 g/mol
Synonyms	2-Bromo-4-(phthalimido)butanoic acid; 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-bromobutanoic acid; N-(2-Bromosuccinyl)phthalimide; 2-Bromo-4-phthalimidobutyric acid; γ-Bromo-β-phthalimidopropionic acid; PhthN(CH2)2CHBrCOOH; 2-Bromo-4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanoic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(1,3-Dioxoisoindolin-2-Yl)Butanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports applications requiring reliable and traceable raw materials for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.