Description

(E)-2-Methyl-3-Phenyl-Acryloyl Chloride is a high-purity, reactive acid chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the (E)-2-methylcinnamoyl moiety, enabling the development of novel molecules with specific stereochemistry and functional properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting novel small molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cinnamoyl structure can contribute to biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Liquid Crystal & OLED Materials: A precursor in the synthesis of organic electronic materials due to its conjugated system and reactive handle.
• Peptide & Protein Modification: Employed as an acylating agent for modifying amino acids or proteins to study structure-activity relationships.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex organic dyes and pigments.
• Flavor & Fragrance Compounds: Used in the synthesis of certain aroma chemicals that benefit from the phenylpropenoid backbone.
• Academic & Contract Research: Essential reagent for methodological development and novel synthetic route exploration in R&D laboratories.

Basic Information

Product Name	(E)-2-Methyl-3-Phenyl-Acryloyl Chloride
CAS No.	35086-87-4
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	(E)-2-Methylcinnamoyl Chloride; trans-2-Methylcinnamoyl Chloride; (E)-3-Phenyl-2-butenoyl Chloride; 2-Methyl-3-phenylpropenoyl Chloride; (E)-2-Methyl-3-phenyl-2-propenoyl Chloride; Atropic Acid Chloride (related); (E)-α-Methylcinnamoyl Chloride
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-3-Phenyl-Acryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.