Description

Tetramethyl Pyrazine-2,3,5,6-Tetracarboxylate is a high-purity, multi-functional organic building block and intermediate of significant commercial interest. This compound is valued for its rigid, symmetrical pyrazine core and four reactive ester groups, which enable its use in the synthesis of complex molecules and advanced materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for applications ranging from ligand synthesis to the creation of novel functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring complex heterocyclic architectures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its derivatizable pyrazine structure.
• Coordination Chemistry & Ligand Synthesis: The tetracarboxylate ester groups can be hydrolyzed to form acids, making it a valuable starting point for creating multidentate chelating ligands for metal-organic frameworks (MOFs) and catalysts.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for the production of specialty polyesters, polyamides, and other high-performance polymers.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal chemistry and chemical research, enabling the exploration of new molecular entities.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments where the pyrazine ring contributes to color and stability.

Basic Information

Product Name	Tetramethyl Pyrazine-2,3,5,6-Tetracarboxylate
CAS No.	35042-21-8
Molecular Formula	C14H14N2O8
Molecular Weight	338.27 g/mol
Synonyms	Pyrazine-2,3,5,6-tetracarboxylic acid tetramethyl ester; Tetramethyl pyrazine-2,3,5,6-tetracarboxylate; 2,3,5,6-Pyrazinetetracarboxylic acid, tetramethyl ester; Methyl pyrazine-2,3,5,6-tetracarboxylate; Pyrazinetetracarboxylic acid tetramethyl ester; Tetramethyl 2,3,5,6-pyrazinetetracarboxylate; 2,3,5,6-Tetrakis(methoxycarbonyl)pyrazine
EINECS	Contact for details

Quality Control

Our Tetramethyl Pyrazine-2,3,5,6-Tetracarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, physical characteristics, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.