Description

Methyl 5-Amino-3,6-Dichloropyrazine-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique pyrazine core, functionalized with amino, chloro, and ester groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Academic & Industrial R&D: A valuable reagent for methodological chemistry research, including cross-coupling reactions and heterocycle functionalization studies.

Basic Information

Product Name	Methyl 5-Amino-3,6-Dichloropyrazine-2-Carboxylate
CAS No.	34617-69-1
Molecular Formula	C7H5Cl2N3O2
Molecular Weight	236.04 g/mol
Synonyms	5-Amino-3,6-dichloro-2-pyrazinecarboxylic acid methyl ester; Methyl 5-amino-3,6-dichloro-2-pyrazinecarboxylate; 3,6-Dichloro-5-aminopyrazine-2-carboxylic acid methyl ester; 2-Pyrazinecarboxylic acid, 5-amino-3,6-dichloro-, methyl ester; 5-Amino-3,6-dichloropyrazine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-3,6-Dichloropyrazine-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings (e.g., Drug Master Files).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.