Description

(3Ar)-4,4A,7Aα,8,9,9Aα-Hexahydro-4α-(Isovaleryloxy)-3β,4Aβ,8α-Trimethylazuleno[6,5-B]Furan-2,5(3H,3Aαh)-Dione is a complex, high-purity sesquiterpene lactone derivative with a unique azulene-fused furanone structure. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules, offering significant value in research and development. It is primarily sought by pharmaceutical R&D laboratories and specialty chemical manufacturers focused on developing new therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and anticancer research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities based on the azulene and sesquiterpene scaffolds.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and compound identification.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fragrance ingredients or specialty agrochemicals.
• Academic & Institutional Research: Utilized in universities and research institutes for studying natural product derivatives and their chemical properties.

Basic Information

Product Name	(3Ar)-4,4A,7Aα,8,9,9Aα-Hexahydro-4α-(Isovaleryloxy)-3β,4Aβ,8α-Trimethylazuleno[6,5-B]Furan-2,5(3H,3Aαh)-Dione
CAS No.	34532-66-6
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	4α-(Isovaleryloxy)-3β,4aβ,8α-trimethyl-4,4a,7aα,8,9,9aα-hexahydroazuleno[6,5-b]furan-2,5(3H,3aαH)-dione; 3β,4aβ,8α-Trimethyl-4α-(3-methylbutanoyloxy)-4,4a,7aα,8,9,9aα-hexahydroazuleno[6,5-b]furan-2,5(3H,3aαH)-dione; Alantolactone isovalerate (related derivative); Isoalantholactone isovalerate; Azuleno[6,5-b]furan-2,5-dione derivative; Sesquiterpene lactone isovalerate ester.
EINECS	Contact for details

Quality Control

Our (3Ar)-4,4A,7Aα,8,9,9Aα-Hexahydro-4α-(Isovaleryloxy)-3β,4Aβ,8α-Trimethylazuleno[6,5-B]Furan-2,5(3H,3Aαh)-Dione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to confirm identity and purity, ensuring it meets the stringent requirements for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.