Description

Senegin II is a bioactive saponin compound derived from the roots of *Polygala senega* L. This high-purity phytochemical is valued for its consistent quality and reliable biological activity, making it a critical reference standard and research material. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and life science sectors for analytical, pharmacological, and product development purposes.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal extracts and finished products containing senega root.
• Biochemical Research: Serves as a key reagent in studies investigating the pharmacological properties of saponins, including expectorant, anti-inflammatory, and immunomodulatory activities.
• Natural Product Isolation & Analysis: Employed as a marker compound in the development and validation of analytical methods (e.g., HPLC, LC-MS) for the identification and quantification of saponins in complex botanical matrices.
• Nutraceutical Development: Acts as a standardized bioactive ingredient or a benchmark for potency in the formulation of dietary supplements targeting respiratory health.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research on plant secondary metabolites and their structure-activity relationships.

Basic Information

Product Name	Senegin II
CAS No.	34366-31-9
Molecular Formula	C59H96O27
Molecular Weight	1221.4 g/mol
Synonyms	Senegin-II; Polygalasaponin XXX; Senegin 2; Senegin B; Presenegenin 3-O-β-D-glucopyranosyl-(1→4)-β-D-fucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→4)-β-D-fucopyranoside; (3β,4α,16α)-3-[[4-O-[4-O-(β-D-Glucopyranosyl)-β-D-fucopyranosyl]-β-D-glucopyranosyl]oxy]-16-hydroxy-28-oxoolean-12-en-23-oic acid β-D-fucopyranosyl ester
EINECS	Contact for details

Quality Control

Our Senegin II is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (TLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.