Description

(S)-3-Aminopiperidine-2-One CAS NO 34294-79-6 is a high-purity chiral piperidinone derivative, serving as a critical building block in modern organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, essential for achieving desired biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent drug candidates, including protease inhibitors and receptor modulators.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective reactions to create enantiomerically pure compounds.
• Peptidomimetics Research: Incorporated into the backbone of peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Development: Serves as a building block for creating novel, chiral active ingredients with specific modes of action.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high chiral purity and reliable supply.

Basic Information

Product Name	(S)-3-Aminopiperidine-2-One
CAS No.	34294-79-6
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(S)-3-Amino-2-piperidone; (3S)-3-Amino-2-piperidinone; (S)-3-Amino-delta2-piperidinone; (S)-3-Aminopiperidin-2-one; (S)-3-Azanylpiperidin-2-one; L-3-Aminopiperidin-2-one; (S)-2-Oxo-3-aminopiperidine; (S)-3-Amino-2-oxopiperidine
EINECS	Contact for details

Quality Control

Our (S)-3-Aminopiperidine-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.