Description

(+/-)-9-Hydroxy-10E,12Z-Octadecadienoic Acid, Cholesteryl Ester is a specialized biochemical derivative, combining a hydroxy-conjugated linoleic acid (CLA) moiety with a cholesterol backbone. This compound is of significant interest for research into lipid metabolism, cellular signaling, and the development of bioactive agents. It serves as a critical intermediate and reference standard for scientists and manufacturers in the pharmaceutical, nutraceutical, and advanced life science sectors.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies of lipid oxidation, eicosanoid pathways, and cholesterol metabolism.
• Pharmaceutical Development: Investigated as a potential precursor or active pharmaceutical ingredient (API) in formulations targeting inflammatory and metabolic disorders.
• Nutraceutical & Cosmetic Actives: Explored for incorporation into advanced dietary supplements and topical formulations for its potential bioactive properties.
• Analytical Chemistry: Serves as a high-purity calibration standard for analytical methods such as HPLC, GC-MS, and LC-MS in lipidomics.
• Cell Biology & Signaling Studies: Utilized in vitro to study the effects of modified lipoproteins and oxysterols on cell membrane function and receptor interactions.

Basic Information

Product Name	(+/-)-9-Hydroxy-10E,12Z-Octadecadienoic Acid, Cholesteryl Ester
CAS No.	33783-76-5
Molecular Formula	C45H78O3
Molecular Weight	667.1 g/mol
Synonyms	9-Hydroxy-10E,12Z-octadecadienoic acid cholesteryl ester; 9-Hydroxy-cis-10,trans-12-octadecadienoic acid cholesterol ester; Cholesteryl 9-hydroxy-10E,12Z-octadecadienoate; 9-OH-10E,12Z-CLA cholesteryl ester; Cholesterol 9-hydroxyconjugated linoleate; 9-Hydroxy CLA cholesterol ester; (±)-9-Hydroxy-10-trans,12-cis-octadecadienoic acid cholesteryl ester
EINECS	Contact for details

Quality Control

Our (+/-)-9-Hydroxy-10E,12Z-Octadecadienoic Acid, Cholesteryl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. The compound is sensitive to strong acids and organic solvents; handle with appropriate precautions in a well-ventilated area. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.