Description

Cobyrinic Acid is a key intermediate in the biosynthesis of vitamin B12 (cobalamin) and related corrinoids. This compound matters significantly for its role as a foundational precursor in the production of high-value biochemicals and pharmaceuticals. It is primarily needed by manufacturers in the pharmaceutical, fine chemical, and research sectors for synthesizing cobalamin derivatives and developing novel enzymatic pathways.

Application

• Vitamin B12 Synthesis: A crucial biosynthetic precursor in the commercial and research-scale production of cyanocobalamin, methylcobalamin, and other cobalamin forms.
• Pharmaceutical Intermediates: Used in the manufacture of active pharmaceutical ingredients (APIs) where the corrinoid structure is required for biological activity.
• Biochemical Research: Serves as a standard and starting material in metabolic pathway studies, enzyme mechanism investigations, and microbiology research related to cobalamin biosynthesis.
• Fine Chemical Production: Employed as a building block for synthesizing specialized corrinoid-based catalysts and complex organic molecules.
• Nutraceutical Development: Used in R&D for creating novel vitamin B12 analogs and fortified products.
• Microbial Fermentation Studies: Applied in research to understand and optimize vitamin B12 production in microorganisms like *Propionibacterium* and *Pseudomonas*.

Basic Information

Product Name	Cobyrinic Acid
CAS No.	33593-50-9
Molecular Formula	C46H64N4O14
Molecular Weight	897.02 g/mol
Synonyms	Cobyrinic acid; Cobyrinic acid a,c-diamide; Cobyrinic acid a,c-diamide, (aR)-isomer; Vitamin B12 precursor; Corrinoid intermediate; 8,13-Diethyl-2,7,12,17-tetramethyl-3,18-divinylcorrin-2,7,12,17-tetrapropionic acid
EINECS	Contact for details

Quality Control

Our Cobyrinic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Reddish-brown to dark red powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.