Description

3-Methyl-1,2,4-triazolo[4,3-a]pyrazine is a high-purity, nitrogen-rich heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its fused triazolopyrazine structure makes it a valuable intermediate for developing novel pharmaceuticals and agrochemicals with targeted biological activity. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Serves as a nitrogen-donor ligand or precursor in the development of specialized polymers, coordination complexes, and electronic materials.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies in drug discovery programs.
• Fine Chemical Synthesis: Utilized as a versatile building block for constructing complex, polyheterocyclic systems of commercial and research interest.

Basic Information

Product Name	3-Methyl-1,2,4-triazolo[4,3-a]pyrazine
CAS No.	33590-17-9
Molecular Formula	C6H6N4
Molecular Weight	134.14 g/mol
Synonyms	3-Methyl-1,2,4-triazolopyrazine; 3-Methyl-[1,2,4]triazolo[4,3-a]pyrazine; 1,2,4-Triazolo[4,3-a]pyrazine, 3-methyl-; 3-Methyl-1,2,4-triazolo[4,3-a]pyrazin; 3-Methyl-1,2,4-triazolo(4,3-a)pyrazine
EINECS	Contact for details

Quality Control

Our 3-Methyl-1,2,4-triazolo[4,3-a]pyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.