Description

(14R)-Grayanotoxane-3β,5,6β,7α,10,14,16-Heptol 6-Acetate 7-Propanoate is a highly functionalized diterpenoid natural product derivative, specifically a grayanotoxin analog. This compound is of significant interest for advanced research and development due to its complex polyhydroxylated structure and specific ester modifications. It serves as a critical reference standard and a valuable chemical intermediate for pharmaceutical discovery, toxicology studies, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of grayanotoxin-related compounds in drug development and quality control laboratories.
• Biochemical Research: Acts as a key intermediate or probe in studies investigating sodium channel modulation and neurotoxicological mechanisms.
• Natural Product Synthesis: Serves as a sophisticated building block for the semi-synthesis of novel diterpenoid derivatives with potential biological activity.
• Analytical Chemistry: Employed as a high-purity calibrant in chromatographic methods (HPLC, LC-MS) for method development and validation.
• Toxicology and Safety Assessment: Utilized in research to understand the metabolic pathways and toxicological profiles of grayanotoxins.

Basic Information

Product Name	(14R)-Grayanotoxane-3β,5,6β,7α,10,14,16-Heptol 6-Acetate 7-Propanoate
CAS No.	33476-74-3
Molecular Formula	C25H38O9
Molecular Weight	482.57 g/mol
Synonyms	Grayanotoxin III 6-Acetate 7-Propanoate; Grayanotoxin III Diacyl Derivative; (14R)-Grayanotoxane-3,5,6,7,10,14,16-heptol 6-acetate 7-propanoate; 6-Acetyl-7-propionylgrayanotoxin III; 3,5,6,7,10,14,16-Heptahydroxygrayanotoxane 6-acetate 7-propionate; Andromedotoxin derivative; Acetylpropionylgrayanotoxin III
EINECS	Contact for details

Quality Control

We supply this high-value compound with a focus on identity confirmation and purity assurance. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chromatographic profile is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The compound may be light-sensitive and hygroscopic; handle under inert atmosphere when appropriate.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0% (KF)
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.