Description

Zomepirac CAS NO 33369-31-2 is a non-steroidal anti-inflammatory drug (NSAID) belonging to the pyrrole acetic acid class, historically used for its potent analgesic and anti-inflammatory properties. Its significance lies in its role as a key reference compound and intermediate in pharmaceutical research and development. This product is essential for research laboratories, analytical chemists, and manufacturers engaged in the synthesis of novel therapeutic agents, method development, and quality control testing within the pharmaceutical and life sciences sectors.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method validation, quality control, and regulatory compliance in drug testing.
• Active Pharmaceutical Ingredient (API) Intermediate: Used as a critical building block in the research-scale synthesis of novel anti-inflammatory compounds and prodrugs.
• Biochemical Research: Employed in pharmacological studies to investigate cyclooxygenase (COX) inhibition pathways and the mechanisms of NSAID action.
• Analytical Chemistry: Utilized as a high-purity standard for calibrating instruments (HPLC, GC-MS) and developing assays in forensic and clinical toxicology.
• Academic Research: A vital reagent for universities and institutions conducting studies in medicinal chemistry, pharmacology, and drug metabolism.

Basic Information

Product Name	Zomepirac
CAS No.	33369-31-2
Molecular Formula	C15H14ClNO3
Molecular Weight	291.73 g/mol
Synonyms	Zomepirac; McN-2783-21-98; CL-71563; 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid; (1,4-Dimethyl-5-(4-chlorobenzoyl)-1H-pyrrol-2-yl)acetic acid
EINECS	251-477-7

Quality Control

Our Zomepirac is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC-MS to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) containing batch-specific data is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.