Description

Gliquidone is a second-generation sulfonylurea compound used as an oral anti-diabetic agent. It is valued for its potent hypoglycemic effect, stimulating insulin secretion from pancreatic beta cells. This active pharmaceutical ingredient (API) is essential for the formulation of medications targeting type 2 diabetes mellitus. Pharmaceutical manufacturers and research institutions globally rely on high-purity Gliquidone CAS NO 33342-05-1 for drug development and production.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral anti-diabetic tablets and capsules for managing type 2 diabetes.
• Drug Formulation R&D: Utilized in research and development for new dosage forms, including controlled-release and combination drug therapies.
• Reference Standard: Serves as a high-purity chemical reference standard in analytical laboratories for quality control and method validation.
• Clinical Research: Employed in preclinical and clinical studies to investigate pharmacokinetics, efficacy, and new therapeutic applications.
• Generic Drug Manufacturing: A key component in the production of generic versions of branded sulfonylurea medications.

Basic Information

Product Name	Gliquidone
CAS No.	33342-05-1
Molecular Formula	C27H33N3O6S
Molecular Weight	527.63 g/mol
Synonyms	1-Cyclohexyl-3-[[p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]phenyl]sulfonyl]urea; AR-DF 26; Gliquidon; Glurenorm; Glurenor; M 5276; McN 3495; McN-3495; Beglynor; Gliquidona; Gliquidonum
EINECS	Contact for details

Quality Control

Our Gliquidone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide detailed Certificates of Analysis (COA) that include results for identity, purity, and specified impurities. Quality is assured through compliance with current Good Manufacturing Practices (cGMP) and relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.