Description

5-Methoxy-2-Chloropyrazine is a versatile heterocyclic building block with a distinct pyrazine core functionalized with methoxy and chloro substituents. This compound is valued for its role as a key synthetic intermediate in the production of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active ingredients, fine chemicals, and advanced materials who require a reliable supply of high-purity intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyrazine scaffold for biological activity.
• Fine Chemical Production: Serves as a building block for creating complex organic compounds used in dyes, pigments, and electronic chemicals.
• Material Science Research: Employed in the development of organic semiconductors, ligands for catalysis, and other advanced functional materials.
• Academic & R&D: A valuable reagent for medicinal chemistry and organic synthesis research in university and industrial laboratories.

Basic Information

Product Name	5-Methoxy-2-Chloropyrazine
CAS No.	33332-31-9
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	2-Chloro-5-methoxypyrazine; 5-Methoxy-2-chloropyrazine; 2-Chloro-5-methoxypyrazine; 5-Methoxypyrazine, 2-chloro-; 2-Chloro-5-methoxy-1,4-diazine; NSC 403120
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Chloropyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.