Description

2-Amino-5-Chloropyrazine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique pyrazine core functionalized with both amino and chloro groups makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for creating labeled compounds or probes for studying biological mechanisms.
• Custom Synthesis and Scale-up: A fundamental substrate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke chemicals for clients.

Basic Information

Item	Details
Product Name	2-Amino-5-Chloropyrazine
CAS No.	33332-29-5
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	5-Chloro-2-pyrazinamine; 5-Chloropyrazin-2-amine; 2-Amino-5-chloropyrazine; 5-Chloro-2-aminopyrazine; 2-Pyrazinamine, 5-chloro-; 5-Chloro-2-pyrazinylamine; 2-Amino-5-chloro-1,4-diazine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloropyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data with each shipment. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are compliant with standard industry documentation practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent oxidation and moisture uptake for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.