Description

2-Chloro-6-Aminopyrazine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and amino substituents on the pyrazine ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other advanced functional materials.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial Research: Utilized in exploratory chemistry to develop new synthetic methodologies and novel chemical libraries for screening.

Basic Information

Product Name	2-Chloro-6-Aminopyrazine
CAS No.	33332-28-4
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	6-Amino-2-chloropyrazine; 2-Chloro-6-pyrazinamine; 2-Chloropyrazin-6-amine; 2-Chloro-6-aminopyrazine; 6-Amino-2-chloro-1,4-diazine; 2-Chloro-1,4-diazin-6-amine; Aminochloro pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Aminopyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.