Description

K-Strophanthoside is a cardiac glycoside derived from the seeds of *Strophanthus kombé*, known for its potent effects on myocardial contractility. This high-purity compound is critical for research and development in cardiovascular pharmacology and drug discovery. It serves as a vital reference standard and active pharmaceutical ingredient (API) intermediate for pharmaceutical manufacturers, research institutions, and analytical laboratories globally.

Application

• Pharmaceutical Reference Standard: Used for the calibration, validation, and quality control of analytical methods in pharmaceutical testing.
• Cardiovascular Research: A key tool in biochemical and pharmacological studies investigating cardiac muscle function, sodium-potassium ATPase inhibition, and inotropy.
• API Intermediate: Serves as a critical starting material or intermediate in the synthesis of more complex cardiac therapeutic agents.
• Biochemical Assays: Employed in enzyme inhibition studies and receptor binding assays to study mechanisms of cardiac glycoside action.
• Academic & Clinical Research: Supports fundamental research in universities, hospitals, and contract research organizations (CROs) exploring heart failure treatments.

Basic Information

Product Name	K-Strophanthoside
CAS No.	33279-57-1
Molecular Formula	C36H54O14
Molecular Weight	710.81 g/mol
Synonyms	K-Strophanthoside; Strophanthoside K; Kombetin; Cymarin 6'-O-β-D-glucoside; Strophosid; NSC 406312; Strophanthin K; 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-card-20(22)-enolide 6-O-β-D-glucopyranoside
EINECS	Contact for details

Quality Control

Our K-Strophanthoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.