Description

S-(+)-Fenoprofen is the pharmacologically active enantiomer of the non-steroidal anti-inflammatory drug (NSAID) fenoprofen. This high-purity chiral intermediate is critical for the development of enantiomerically pure pharmaceuticals, ensuring targeted therapeutic efficacy and minimizing potential side effects. It is primarily required by pharmaceutical R&D laboratories and manufacturers specializing in advanced analgesic and anti-inflammatory drug formulations.

Application

• Key chiral building block for the synthesis of enantiopure S-(+)-Fenoprofen calcium, the active pharmaceutical ingredient (API).
• Critical reference standard and impurity standard in pharmaceutical quality control and analytical method development (HPLC, GC).
• Intermediate in advanced research on COX enzyme inhibitors and structure-activity relationship (SAR) studies.
• Starting material for the preparation of novel prodrugs and drug conjugates to improve bioavailability.
• Used in pharmacological studies to investigate the stereoselective metabolism and pharmacokinetics of NSAIDs.

Basic Information

Product Name	S-(+)-Fenoprofen
CAS No.	33028-97-6
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	(S)-(+)-2-(3-Phenoxyphenyl)propionic Acid; (S)-Fenoprofen; (+)-Fenoprofen; Dexfenoprofen; (S)-2-(3-Phenoxyphenyl)propanoic Acid; (S)-3-Phenoxyhydratropic Acid; (2S)-2-(3-Phenoxyphenyl)propanoic Acid; NSC 339015
EINECS	Contact for details

Quality Control

Our S-(+)-Fenoprofen is manufactured under strict quality systems to ensure high enantiomeric and chemical purity suitable for pharmaceutical research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines and can provide material with specifications tailored to your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (S-Isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.