Description

Tris(Diethylamino)Difluorophosphorane is a highly reactive organophosphorus compound that serves as a versatile reagent in advanced chemical synthesis. Its primary value lies in its ability to act as a potent fluorinating and aminating agent, facilitating the introduction of fluorine and diethylamino groups into complex molecular frameworks. This makes it an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the fluorination and functionalization of drug candidates, especially in nucleoside and nucleotide chemistry.
• Agrochemical Production: Used in the synthesis of advanced pesticides and herbicides where the introduction of fluorine atoms enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing phosphorus-based ligands used in homogeneous catalysis.
• Polymer Chemistry: Employed in the modification of polymers and the creation of flame-retardant or specialty polymeric materials.
• Material Science Research: Utilized in the development of novel fluorinated materials, including surface modifiers and electronic chemicals.
• Organic Synthesis Reagent: Acts as a dehydrating agent or a source of the difluorophosphorane moiety in complex organic transformations.

Basic Information

Product Name	Tris(Diethylamino)Difluorophosphorane
CAS No.	32318-29-9
Molecular Formula	C12H30F2N3P
Molecular Weight	285.36 g/mol
Synonyms	Difluorotris(diethylamino)phosphorane; Tris(diethylamino)difluorophosphate; P,P,P-Tris(diethylamino)difluorophosphorane; (Diethylamino)difluorophosphine oxide dimer (related form); TDAFP; Phosphorane, difluorotris(diethylamino)-; 32318-29-9; EINECS 250-999-2
EINECS	250-999-2

Quality Control

Our Tris(Diethylamino)Difluorophosphorane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and production applications. Each lot is analyzed using advanced techniques including NMR, GC, and titration methods to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed and handled under dry conditions to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.