Description

(R)-2-Methylbutyric Acid CAS NO 32231-50-8 is a high-purity chiral organic acid, a key building block in the synthesis of optically active compounds. Its enantiomeric purity is critical for applications where stereochemistry directly influences biological activity, flavor, or fragrance profiles. This product is essential for R&D and production in the pharmaceutical, flavor & fragrance, and advanced agrochemical industries.

Application

• Pharmaceutical Intermediates: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system drugs.
• Flavor and Fragrance Industry: Used as a precursor for esters and other derivatives that impart fruity, cheesy, or savory notes in food flavorings and perfumery.
• Agrochemical Synthesis: Serves as a chiral starting material for producing enantiomerically pure herbicides, pesticides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway analysis.
• Polymer Modification: Acts as a monomer or modifier for introducing specific chiral centers into specialty polymers.

Basic Information

Product Name	(R)-2-Methylbutyric Acid
CAS No.	32231-50-8
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	(R)-2-Methylbutanoic Acid; D-2-Methylbutyric Acid; (R)-(-)-2-Methylbutyric Acid; (2R)-2-Methylbutanoic Acid; (R)-2-Methylbutyrate; D-2-Methylbutanoic Acid; (R)-Sec-Butylformic Acid; (R)-Active Amyl Acid
EINECS	Contact for details

Quality Control

Our (R)-2-Methylbutyric Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This product is a strong acid/organic solvent and is easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Refractive Index (n20D)	1.403 - 1.407
Specific Rotation ([α]20D)	-15.0° to -18.0° (c=1, EtOH)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.