Description

5-Methoxypyrazine-2-Carbaldehyde is a versatile heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a pyrazine ring and a formyl group, makes it a critical precursor for constructing complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Serves as a building block for creating new generation pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions and organocatalysts due to its coordinating nitrogen atoms and modifiable aldehyde group.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing pyrazine derivatives that contribute roasted, nutty, or earthy notes in high-value aroma compounds.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) where its planar, conjugated structure is advantageous.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	5-Methoxypyrazine-2-Carbaldehyde
CAS No.	32205-72-4
Molecular Formula	C6H6N2O2
Molecular Weight	138.12 g/mol
Synonyms	2-Formyl-5-methoxypyrazine; 5-Methoxy-2-pyrazinecarboxaldehyde; 5-Methoxypyrazine-2-carboxaldehyde; 2-Pyrazinecarboxaldehyde, 5-methoxy-; 5-Methoxy-2-pyrazinecarbaldehyde; 5-Methoxypyrazinecarbaldehyde-2; Methoxypyrazinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Methoxypyrazine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.